The NINDS Parkinson's disease biomarkers program.
Identifieur interne : 000045 ( Main/Exploration ); précédent : 000044; suivant : 000046The NINDS Parkinson's disease biomarkers program.
Auteurs : Liana S. Rosenthal [États-Unis] ; Daniel Drake [États-Unis] ; Roy N. Alcalay [États-Unis] ; Debra Babcock [États-Unis] ; F Dubois Bowman [États-Unis] ; Alice Chen-Plotkin [États-Unis] ; Ted M. Dawson [États-Unis] ; Richard B. Dewey [États-Unis] ; Dwight C. German [États-Unis] ; Xuemei Huang [États-Unis] ; Barry Landin [États-Unis] ; Matthew Mcauliffe [États-Unis] ; Vladislav A. Petyuk [États-Unis] ; Clemens R. Scherzer [États-Unis] ; Coryse St Hillaire-Clarke [États-Unis] ; Beth-Anne Sieber [États-Unis] ; Margaret Sutherland [États-Unis] ; Chi Tarn [États-Unis] ; Andrew West [États-Unis] ; David Vaillancourt [États-Unis] ; Jing Zhang [États-Unis] ; Katrina Gwinn [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
Abstract
Neuroprotection for Parkinson's disease (PD) remains elusive. Biomarkers hold the promise of removing roadblocks to therapy development. The National Institute of Neurological Disorders and Stroke has therefore established the Parkinson's Disease Biomarkers Program to promote discovery of PD biomarkers for use in phase II and III clinical trials.
DOI: 10.1002/mds.26438
PubMed: 26442452
Affiliations:
- États-Unis
- Angleterre, Floride, Maryland, Massachusetts, Midlands de l'Ouest, New Jersey, Pennsylvanie, Washington (État), État de New York
- Birmingham, New York, Seattle
- Université Columbia, Université de Washington
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Rosenthal</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Drake, Daniel" sort="Drake, Daniel" uniqKey="Drake D" first="Daniel" last="Drake">Daniel Drake</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biostatistics, Columbia University, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Alcalay, Roy N" sort="Alcalay, Roy N" uniqKey="Alcalay R" first="Roy N" last="Alcalay">Roy N. Alcalay</name><affiliation wicri:level="4"><nlm:affiliation>Department of Neurology, Columbia University, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Babcock, Debra" sort="Babcock, Debra" uniqKey="Babcock D" first="Debra" last="Babcock">Debra Babcock</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Bowman, F Dubois" sort="Bowman, F Dubois" uniqKey="Bowman F" first="F Dubois" last="Bowman">F Dubois Bowman</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biostatistics, Columbia University, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Chen Plotkin, Alice" sort="Chen Plotkin, Alice" uniqKey="Chen Plotkin A" first="Alice" last="Chen-Plotkin">Alice Chen-Plotkin</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Dawson, Ted M" sort="Dawson, Ted M" uniqKey="Dawson T" first="Ted M" last="Dawson">Ted M. 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Petyuk</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Scherzer, Clemens R" sort="Scherzer, Clemens R" uniqKey="Scherzer C" first="Clemens R" last="Scherzer">Clemens R. Scherzer</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Hillaire Clarke, Coryse St" sort="Hillaire Clarke, Coryse St" uniqKey="Hillaire Clarke C" first="Coryse St" last="Hillaire-Clarke">Coryse St Hillaire-Clarke</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Sieber, Beth Anne" sort="Sieber, Beth Anne" uniqKey="Sieber B" first="Beth-Anne" last="Sieber">Beth-Anne Sieber</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Sutherland, Margaret" sort="Sutherland, Margaret" uniqKey="Sutherland M" first="Margaret" last="Sutherland">Margaret Sutherland</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Tarn, Chi" sort="Tarn, Chi" uniqKey="Tarn C" first="Chi" last="Tarn">Chi Tarn</name><affiliation wicri:level="2"><nlm:affiliation>Coriell Institute for Medical Research, Camden, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Coriell Institute for Medical Research, Camden, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="West, Andrew" sort="West, Andrew" uniqKey="West A" first="Andrew" last="West">Andrew West</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, University of Alabama at Birmingham, Birmingham, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Vaillancourt, David" sort="Vaillancourt, David" uniqKey="Vaillancourt D" first="David" last="Vaillancourt">David Vaillancourt</name><affiliation wicri:level="2"><nlm:affiliation>Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Zhang, Jing" sort="Zhang, Jing" uniqKey="Zhang J" first="Jing" last="Zhang">Jing Zhang</name><affiliation wicri:level="4"><nlm:affiliation>Department of Pathology, University of Washington, Seattle, Washington, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Gwinn, Katrina" sort="Gwinn, Katrina" uniqKey="Gwinn K" first="Katrina" last="Gwinn">Katrina Gwinn</name><affiliation wicri:level="2"><nlm:affiliation>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Neuroprotection for Parkinson's disease (PD) remains elusive. Biomarkers hold the promise of removing roadblocks to therapy development. The National Institute of Neurological Disorders and Stroke has therefore established the Parkinson's Disease Biomarkers Program to promote discovery of PD biomarkers for use in phase II and III clinical trials.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Angleterre</li><li>Floride</li><li>Maryland</li><li>Massachusetts</li><li>Midlands de l'Ouest</li><li>New Jersey</li><li>Pennsylvanie</li><li>Washington (État)</li><li>État de New York</li></region><settlement><li>Birmingham</li><li>New York</li><li>Seattle</li></settlement><orgName><li>Université Columbia</li><li>Université de Washington</li></orgName></list><tree><country name="États-Unis"><region name="Maryland"><name sortKey="Rosenthal, Liana S" sort="Rosenthal, Liana S" uniqKey="Rosenthal L" first="Liana S" last="Rosenthal">Liana S. Rosenthal</name></region><name sortKey="Alcalay, Roy N" sort="Alcalay, Roy N" uniqKey="Alcalay R" first="Roy N" last="Alcalay">Roy N. Alcalay</name><name sortKey="Babcock, Debra" sort="Babcock, Debra" uniqKey="Babcock D" first="Debra" last="Babcock">Debra Babcock</name><name sortKey="Bowman, F Dubois" sort="Bowman, F Dubois" uniqKey="Bowman F" first="F Dubois" last="Bowman">F Dubois Bowman</name><name sortKey="Chen Plotkin, Alice" sort="Chen Plotkin, Alice" uniqKey="Chen Plotkin A" first="Alice" last="Chen-Plotkin">Alice Chen-Plotkin</name><name sortKey="Dawson, Ted M" sort="Dawson, Ted M" uniqKey="Dawson T" first="Ted M" last="Dawson">Ted M. Dawson</name><name sortKey="Dewey, Richard B" sort="Dewey, Richard B" uniqKey="Dewey R" first="Richard B" last="Dewey">Richard B. Dewey</name><name sortKey="Drake, Daniel" sort="Drake, Daniel" uniqKey="Drake D" first="Daniel" last="Drake">Daniel Drake</name><name sortKey="German, Dwight C" sort="German, Dwight C" uniqKey="German D" first="Dwight C" last="German">Dwight C. German</name><name sortKey="Gwinn, Katrina" sort="Gwinn, Katrina" uniqKey="Gwinn K" first="Katrina" last="Gwinn">Katrina Gwinn</name><name sortKey="Hillaire Clarke, Coryse St" sort="Hillaire Clarke, Coryse St" uniqKey="Hillaire Clarke C" first="Coryse St" last="Hillaire-Clarke">Coryse St Hillaire-Clarke</name><name sortKey="Huang, Xuemei" sort="Huang, Xuemei" uniqKey="Huang X" first="Xuemei" last="Huang">Xuemei Huang</name><name sortKey="Landin, Barry" sort="Landin, Barry" uniqKey="Landin B" first="Barry" last="Landin">Barry Landin</name><name sortKey="Mcauliffe, Matthew" sort="Mcauliffe, Matthew" uniqKey="Mcauliffe M" first="Matthew" last="Mcauliffe">Matthew Mcauliffe</name><name sortKey="Petyuk, Vladislav A" sort="Petyuk, Vladislav A" uniqKey="Petyuk V" first="Vladislav A" last="Petyuk">Vladislav A. Petyuk</name><name sortKey="Scherzer, Clemens R" sort="Scherzer, Clemens R" uniqKey="Scherzer C" first="Clemens R" last="Scherzer">Clemens R. Scherzer</name><name sortKey="Sieber, Beth Anne" sort="Sieber, Beth Anne" uniqKey="Sieber B" first="Beth-Anne" last="Sieber">Beth-Anne Sieber</name><name sortKey="Sutherland, Margaret" sort="Sutherland, Margaret" uniqKey="Sutherland M" first="Margaret" last="Sutherland">Margaret Sutherland</name><name sortKey="Tarn, Chi" sort="Tarn, Chi" uniqKey="Tarn C" first="Chi" last="Tarn">Chi Tarn</name><name sortKey="Vaillancourt, David" sort="Vaillancourt, David" uniqKey="Vaillancourt D" first="David" last="Vaillancourt">David Vaillancourt</name><name sortKey="West, Andrew" sort="West, Andrew" uniqKey="West A" first="Andrew" last="West">Andrew West</name><name sortKey="Zhang, Jing" sort="Zhang, Jing" uniqKey="Zhang J" first="Jing" last="Zhang">Jing Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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